the testis-specific proteasome subunit prosa6t of drosophila melanogaster is required for individualization and nuclear maturation during spermatogenesis

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Answer 1

The testis-specific proteasome subunit prosa6t of drosophila melanogaster is required for individualization and nuclear maturation during spermatogenesis melanogaster is required.

In eukaryotes, the 26S proteasome is responsible for the majority of controlled proteolysis. An end-cap regulatory particle and a catalytic core particle make up this big, multisubunit complex. A third of the 32 proteasome subunits discovered in Drosophila contain isoforms that are unique to the testis and are encoded by paralogous genes. Here, we characterise the Prosalpha6 (Pros35) core particle subunit and its Prosalpha6T testis-specific variant in detail during spermatogenic expression. Using transgenes with the GFP tag, it is demonstrated that the testis-specific Prosalpha6T becomes prominent in spermatid nuclei and cytoplasm after meiosis and persists in mature sperm, in contrast to the Prosalpha6 subunit, which is expressed in the early stages of spermatogenesis before gradually disappearing after meiosis.

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Related Questions

using advanced bioinformatics tools to identify novel therapeutic candidates for age-related macular degeneration.

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We can use advanced bioinformatics tools to treat Age-related macular degeneration (AMD) is the eye disease that can blur your central vision. It happens only when the aging causes damage to the macula — all the part of the eye that is controls sharp, to straight-ahead vision. The macula is also the part of the retina (the light-sensitive tissue at the back of the eye).

An Age-related macular degeneration can also result in severe loss of the central vision but they rarely causes the blindness. It can, however, make it the difficult to read, to drive or to perform the other daily activities that can require fine central vision. the Age-related macular degeneration is also the leading cause of the vision loss in older adults. Although AMD that doesn't cause the complete blindness, the loss of the central vision and can make it harder to do the everyday tasks. so Dry AMD, a condition that is also causes by the gradual vision loss, is the most common form.

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An ecologist studying desert plants performed the following experiment. She staked out two identical plots, containing sagebrush plants and small annual wildflowers. She found the same five wildflower species in roughly equal numbers on both plots. She then enclosed one plot with a fence to keep out kangaroo rats, the most common grain-eaters of the area. After two years, four of the wildflower species were no longer present in the fenced plot, but one species had become much more abundant. The control plot had not changed in species diversity. Using the principles of community ecology, propose a hypothesis to explain her results. What additional evidence would support your hypothesis?

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The additional evidence that would support your hypothesis is the place where both living and nonliving things present and interact with each other.

How to illustrate the information?

This illustration demonstrates how plant predatory behavior affects the choice of species. The choice of plants in the enclosed area is not influenced by animal predation.

Only other plants will fight for resources in this situation, and one plant had a selection advantage over the other three plant species. The ratio of the four species is the same in the plot that is subject to animal exploitation.

This is probably a result of animals' greater preference for the dominant plant species in the enclosed plot and/or the other three species' anti-animal predation strategies.

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Which technique is dependent upon the release of oxygen from hemoglobin molecules?

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fMRI technique is dependent upon the release of oxygen from hemoglobin molecules

fMRI is a powerful tool for studying brain activity, but it is dependent on the release of oxygen from hemoglobin molecules. This means that any condition that affects oxygen release can potentially impact the results of an fMRI scan.

One condition that can affect oxygen release is anemia. Anemia is a condition in which the blood is unable to carry enough oxygen to meet the body's needs. This can lead to a decrease in the amount of oxygen that is released from hemoglobin molecules, and this can in turn lead to less activity being detected by fMRI.

Anemia is just one example of a condition that can potentially impact fMRI results. It's important to be aware of this when interpreting fMRI data, as it can help to ensure that the results are accurate.

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In which wedge of the two circle graphs do you observe the greatest difference between
the two regions?

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Answer:

Explanation:

a.had to guess but there you go

Glucose is broken down in most of your cells to form carbon dioxide, oxygen, and the energy currency of the cell called atp. what type of chemical reaction is this?

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Glucose is broken down in most of your cells to form carbon dioxide, oxygen, and the energy currency of the cell called   is Catabolic reaction

 Since the energy is released by the breakdown of glucose it is a exothermic reaction.

Catabolic reaction big molecule gets converted into small molecules it is a catabolic reactionCatabolic reaction is when a chemical reaction that results in the break-down of more complex organic molecules into simpler substances and Release energyAnabolism is a chemical reaction in which simpler substances are combined to form more complex molecules and Requires energyCatabolic reaction provides Energy and building blocks for anabolism

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If an injury tore a small hole in the membranes surrounding your lungs, what effect on lung function would you expect?

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Pneumothorax is the result of a tiny hole developing in the lungs' membrane. The inner and outer layers of the lungs could collapse, allowing air to pass through.

The pleural membrane encloses and safeguards the lungs, shielding them from the environment. The superficial layer, commonly known as the parietal pleura, is part of the thoracic cavity wall.Visceral pleura make up the lungs' innermost layer, and the area between them is known as the pleural cavity. It demonstrates the fluid's presence, which lessens friction.A person who has holes in their lungs or lung membranes as a result of trauma or a serious respiratory infection develops respiratory distress syndrome. These injuries may result in air entering the lungs. The ailment is known as pneumothorax. The body couldn't get the necessary amount of oxygen from the lungs.Pneumothorax symptoms include chest pain, coughing, a faster heartbeat, and shortness of breath. The pressure created by the air leak causes the lungs to collapse.

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quantification of gait parameters in freely walking wild type and sensory deprived drosophila melanogaster

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Drosophila melanogaster use a combination of an optical touch sensor and high-speed video imaging to track their body as they walk, and also to record where and when they place each of their six feet on the surface.

In vertebrates and multi-legged invertebrates like Drosophila melanogaster, coordinated walking requires a sophisticated brain network connected to sensory feedback. Systems that can genetically modify brain activity, like Drosophila, will be helpful in comprehending this network. The fly is tiny, making it difficult to study walking in this system. We created an optical technique combined with high-speed imagery to get over this barrier and enable high temporal and spatial resolution monitoring and quantification of gait metrics in freely moving flies. We offer a thorough description of numerous locomotor characteristics for wild type fruit flies using this method, including gait, tarsal posture, intersegmental and left-right coordination.

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In words, describe how the data differ between the unlimited water and no-water conditions for the following:
(a) Osmolarity of urine

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The osmolality of urine is expressed in milliosmoles per kilogram of water (mOsm/kg).

What is meant by Urine osmolality?

The osmolality of urine is expressed in milliosmoles per kilogram of water (mOsm/kg). A typical result is 500 to 850 mOsm/kg, but it can be slightly higher or lower. The precise standards for normal results may differ depending on your doctor and laboratory.

Large molecules (protein), cells, and casts have little effect on osmolality. Urine osmolality varies depending on the fluid and electrolyte balance of the body as well as the nitrogen content of the diet.

Urine osmolality is also useful in assessing a child with polyuria. A urine osmolality of 150 mOsm/kg indicates a urine concentration defect, such as central or nephrogenic diabetes insipidus, whereas a urine osmolality of 300 to 350, associated with a high specific gravity, indicates osmotic diuresis.

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A drug like nicotine that produces a biological response in the brain is called a?

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Answer:

Agonist

Explanation:

An agonist is a chemical that activates a receptor to produce a biological response.

what is a symptom of too much stress over a long period of time? insomnia insomnia elevated antibodies elevated antibodies hallucinations hallucinations low-grade fever

Answers

Answer:

The answer is insomnia.

Explanation:

"Insomnia" means habitual sleeplessness. Ultimately, becoming restless and unable to maintain one's sleep-wake cycle, which will cause stress overtime.

Which forest harvest method would leave the forest as close to a natural old growth forest as possible?

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The selective harvest method would leave the forest as close to a natural old-growth forest as possible.

Only the ripest coffee cherries are harvested and produced using the selective harvesting method. The unripe ones are left on the tree to continue maturing, while.

Additionally, you may be confident that only the best quality cherries are received because only ripe cherries are chosen. Undoubtedly, ripe coffee cherries provide your cup with a nice and pleasant flavor that meets your preferences. a flavor that is both sweet and natural sugary because the fruit had been allowed to develop its sugar over time.

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Explain why the presence of a capsule or slime layer would benefit a bacterial cell.

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The presence of a capsule or slime layer would benefit a bacterial cell as it helps in protection, adhesion and prevents dehydration.

Capsule is the outer layer present in many bacterial cells. It is a part of the cell envelope, which is made up of polysaccharides. It is not easy to get rid of this layer and it can  also a cause of various diseases. The capsule also protects the bacterial cell from being engulfed by the white blood cells.

Dehydration is the condition when the an organism's body lacks the required amount of water of fluids. Bacterial cells can also suffer from dehydration, however they have extreme capacity to survive dehydration for long period of times. The slime or capsule layer also prevent the water loss, preventing dehydration.

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_______________________________ asserts that our genes set the boundaries within which we can operate, and our environment interacts with the genes to determine where in that range we will fall.

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Range of reaction asserts that our genes set the boundaries within which we can operate, and our environment interacts with the genes to determine where in that range we will fall.

What is the relationship between genes and the environment?

Subtle genetic variations might lead one individual to react differently to the same environmental exposure as another. As a consequence, while some people may get an illness as a result of being exposed to something in the environment, others may not.

The notion of range of reaction states that genes impose certain boundaries on potential, and the environment determines how much of that potential is realised. The notion of genetic environmental correlation is another viewpoint on the relationship between genes and the environment.

Genes, through their impacts on morphology and physiology, form a framework within which the environment functions to define an individual animal's behaviour.

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How could the nervous system cause a skeletal muscle to produce the most forceful contraction it is capable of?

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By triggering action potentials from every single motor neuron that regulates the muscle at a rate that causes tetanus in every fiber.

What are motor neurons, and what are they used for?

The central nervous system includes motor neurons, which are cells that transmit instructions from the nerves and muscles that control our movements, speech, swallowing, and breathing.

What makes it a motor neuron?

Motor neurons (also referred to as efferent neurons) are indeed the nerve cells responsible for carrying signals part of the peripheral nervous system towards muscles to cause movement. Neurotransmitters are released by them to set off reactions that cause muscle movement..

In the body, how many motor neurons are there?

There are around 500,000 of them, carrying information first from CNS to peripheral effectors throughout the peripheral tissues but instead organ systems. Motor neuron axons, or efferent fibers, convey information away from the central nervous system..

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In the frog embryo, convergent extension elongates the notochord. Explain how the words convergent and extension apply to this process.

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Convergence and extension coexist in the frog embryo. In the frog's embryo, united expansion prolongs the notochord.

The notochord's cells converge as a result of moving inward, or toward the center of the embryo. The notochord then extends or elongates due to the cells' subsequent reorganization.

Organogenesis is the process by which the embryo's germ layers create primary organs. In some animals, the germ layer cells have specific functions, and as a result, their future is predestined. However, it is not always the case with all creatures.

The cells of the frog embryo display convergent extension, a type of morphogenic movement or rearrangement. The cells reorient themselves toward the midline and converge due to this type of morphogenic migration.

The notochord extends due to the cells' subsequent self-reorganization by cell lengthening and narrowing.

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For subjects in the short protocol, what was the mean ACTH level at waking? Using the data in the last two columns, calculate the mean level 30 minutes later. Was the rate of change faster or slower in that 30-minute period than during the interval from 1: 00 to 6:00 a.m.?

Answers

The rate of change faster or slower in that -

Between 1:00 and 6:00 a.m., the rate of change was (37.3 - 9.9)/5 = 5.5 pg/mL/hr. In the short protocol participants, the rate of change occurred more quickly in the first 30 minutes after awakening than it did between 1:00 and 6:00 am.

The morning (6 to 8 am) is when ACTH levels are at their highest, and the evening (late) is when they are at their lowest (6 pm to 11 pm). If they suspect abnormal levels, a doctor may check the ACTH levels in the morning or evening. ACTH and cortisol levels are usually assessed together.The timing of ACTH secretion may be influenced by a person's expectation of waking up at a particular time. 15 healthy participants in their mid-20s had their mean levels of ACTH measured over the course of three nights to evaluate the influence of anticipation.Both the anticipated and actual wake-up times for the experiment in the short protocol are 6 am. The mean value in the subsequent 30 minutes after walking is 10.6 at the same time.

The rate of change in the first half hour after awakening was equal to 21.2 pg/mL/hr or (10.6 pg/mL)/(0.5 hr). Between 1:00 and 6:00 a.m., the rate of change was (37.3 - 9.9)/5 = 5.5 pg/mL/hr.

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What is a discrete variation that could be changed by the environment or by learning?

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Discrete variation is either/or and is frequently brought on by a select few genes, either present or absent.

One gene, for instance, controls the way we "roll" our tongues. The only options are to roll our tongues or not; there is no middle ground.

Human environmental variables could, for instance, include hair length, or the length at which a person chooses to wear their hair. Scars – from your own unique accidents.

The strength of your muscles depends on how much exercise you get.The many types of variation are dispersed along a continuum in continuous variation. Discontinuous variation, on the other hand, categorizes the many variants into distinct groups.Discrete characteristics like widow's peak and cleft chin are uncommon in humans.

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Every fall, clusters of hundreds of danaus plexippus, or monarch butterflies, migrate into mexico. the traveling group of d. plexippus is one example of a(n) _______. a. population b. ecosystem c. community d. biome please select the best answer from the choices provided a b c d

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Every fall, clusters of hundreds of Danaus plexippus, or monarch butterflies, migrate into Mexico. the travelling group of the population.

It can be also referred to as species.

The greatest collection of organisms that consists of two individuals of the opposing sex or breeding types that may generate offspring that are able to reproduce through sexual reproduction is referred to be a species.

Due to its size and eye-catching orange, black, and white design, the Monarch butterfly species is one that most people are familiar with. It is also remarkable since some of these species migrate for the winter, contrary to the majority of butterflies.

These species, migrate from one location to another for a period of time before returning and repeating the process every year.

Every year, the group of hundreds of Danaus plexippus relocates in pursuit of better environmental circumstances.

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a computer program recognizes an orf by looking for ribosomal binding sites, start codons, and stop codons with an appropriate number of nucleotides between each element. what is a drawback of this approach?

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It's possible to overlook unusual yet functional genes and non-coding RNA.

RNA- All living cells contain ribonucleic acid (RNA), a nucleic acid with properties comparable to those of DNA. However, RNA is often single-stranded, unlike DNA. Instead of the deoxyribose present in DNA, the backbone of an RNA molecule is made up of alternate phosphate groups and the sugar ribose.

Functional genes- A segment of DNA responsible for producing one Polypeptide or another gene product. Thus, the "one cistron" theory replaces the "one gene/one enzyme" idea.

Non-coding RNA- An RNA molecule that does not convert into a protein is known as a non-coding RNA (ncRNA).

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Biologists have found evidence that eukaryotic cells evolved from prokaryotic organisms by a process of intracellular ______.

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Biologists have found evidence that eukaryotic cells evolved from prokaryotic organisms by a process of intracellular symbiosis.

In the field of science, symbiosis can be described as a living together relationship between two species of organisms.

The theory of endosymbiosis suggests how the first eukaryotic cells developed from multiple prokaryotic cells.

Biologists suggest that structures, such as the mitochondria, and chloroplast, existed as prokaryotic cells in the beginning. An intercellular symbiosis relationship such prokaryotic cells was formed afterward which led to the formation of the eukaryotic cell.

Particular pieces of evidence that support the endosymbiotic theory are the existence of own DNA in chloroplast and mitochondria organelles. Also, this particular DNA is circular in the structure like prokaryotes have.

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All blood cells in an adult human can trace their ancestry to which compartment within the body?

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In the red bone marrow of bones, red blood cells are created. Hemocytoblasts are the name for the stem cells found in red bone marrow. All of the blood's formed constituents are produced by them.

From the common lymphoid progenitor, which immune cells are derived?

Common lymphoid progenitor (CLP) cells in the bone marrow give rise to treg cells, which then migrate through the bloodstream to the thymus. Specialized microenvironments are necessary for cellular development. These cells hunt for the autoreactive T cells that have evaded the thymic process of negative selection.

A single type of cell known as a pluripotent cell is the source of all blood cells (also known as a hematopoetic stem cell or a hemocytoblast). Different cell lineages can arise from pluripotent cells.

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Describe the role of countercurrent exchange in facilitating both respiration and thermoregulation (see Concept 40.3).

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Similar to fish, water flows across the gills of geese in the opposite direction of blood through the gill capillaries, promoting fish-like respiration and thermoregulation. As a result, the water extraction along the exchange surfaces is improved.

The process through which an organism's body maintains a steady internal temperature is known as thermoregulation. The majority of birds are homeothermic, which implies that their active metabolic processes help them to keep their body temperatures within a 1°C range.Blood travels through the gills during countercurrent oxygen exchange in the opposite direction from water flowing over them. In contrast, countercurrent exchange enables the blood to absorb 90% of the oxygen in the water.Countercurrent heat exchangers in the blood of geese allow heat to move from warmer to cooler blood, minimizing heat loss. Such animals use bodily insulation and evaporative systems, such sweating and panting, to regulate their body temperature.

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The papillary layer of the dermis is most closely associated with which layer of the epidermis?.

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Answer:

 The papillary layer of the dermis is most closely associated with Stratum Basale layer of the epidermis.

Explanation:

Fibers like collagen and elastin that make up the papillary layer create a loose mesh because this layer is formed of  connective tissue of the areolar that is loose. Dermal papillae, which resemble fingers, are formed when this surface of the dermis extends further to stratum basale of something like the epidermis.   Columnar basal cells, which are continually dividing and also being forced forward towards the surface, may be found in this layer. Additionally, melanocytes that create melanin (the pigment that gives colour to skin) reside inside the stratum basale.  

The various layers of the epidermis regularly regenerate due to epidermal stem cells. . Our hair follicles are constantly renewed because of hair follicle stem cells.

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if one strand of a dna molecule has the sequence of bases 5-attgca-3, the mrna synthesized following the template will be

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If one strand of a DNA molecule has the sequence of bases 5'-ATTGCA-3', the m-RNA synthesized following the template will be 3'-UAACGU-5'.

DNA is the deoxyribonucleic acid. It encodes all the genetic information that describe the traits of a person. DNA is present within the nucleus of the cell. The structure of DNA comprises of two strands that are attached by hydrogen bonds in an alpha-helical manner.

m-RNA is the transcript of DNA formed by the process of transcription. The process takes place in the 5' to 3' direction while the template is read in the opposite direction.  The 5-end of m-RNA is translated first. The template strand is anti-parallel to the newly synthesized m-RNA.

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4. Fruit fly gametes each have four chromosomes
24, or 16, possible chromosome
How many chromosome
combinations could results from fertilization
between a fruit fly egg and a sperm cell?
representing
combinations.
combinations

Answers

There are 256 possible chromosome combinations in total because every sperm and egg has 16 possible chromosome pairings.

Chromosome: what is it?

Chromosomes have formations which resemble threads and house the DNA molecule in each cell's nucleus. Each chromosome is constructed from DNA that has been tightly wound around proteins known as histones numerous times to support its structure.

What use does a chromosome serve?

DNA may be precisely duplicated during these cellular division thanks to chromosomes. So, once more. Our cells' nuclei include chromosomes, which enable precise DNA duplication during cell division. This guarantees that our internal processes go smoothly and effectively.

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A tool that belongs in the heating category is *
O beaker
Otest tube holders
Ostopwatch
O round bottom flask

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Test tube holders, because they hold a test tube while heating it

WRITE ABOUT A THEME: ORGANIZATION In a short essay (100-150 words), explain how the evolution of lignin affected vascular plant structure and function.

Answers

The evolution of lignin affected vascular plant structure and function because it moves water and give strength to the cell wall.

How did the evolution of lignin affect vascular plant structure and function?

Lignin is a type of complex organic polymers that is the key structural substance in the supporting tissues of most plants. Lignin are important in the formation of cell wall in plant cell. Lignin moves water and give strengthens to the cell wall of the plant cell. It is one of the major component of the secondary wall of tall plants. It is produced in the cells that is related to the transport system.

So we can conclude that The evolution of lignin affected vascular plant structure and function because it moves water and give strength to the cell wall.

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Which are characteristics of cachexia? 1. increased appetite 2. weight gain 3. early satiety 4. altered metabolism

Answers

Answer: early satiety

Suppose that a person with damage to the hippocampus is unable to acquire new long-term memories. Why might the acquisition of short-term memories also be impaired?

Answers

In a region of the brain known as the hippocampus, our brain retains a short-term memory of the experience. Later, the memories are “consolidated,” or moved to a different region of the brain, where they will be stored for a longer period of time.

What part of brain is affect in short-term memories?

Alzheimer's disease normally starts by destroying neurons and the connections between them in the cortex and hippocampus, two regions of the brain essential in memory.

Later, it has an impact on the parts of the cerebral cortex that control language, thought, and social interaction.

The frontal lobe of the cerebral cortex is where short-term memory is mostly stored. Then, the information visits the hippocampus for a brief stay.

Therefore, the acquisition of short-term memories also be impaired.

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Photosynthesis provides _____ in the atmosphere that support(s) much of the life on earth.

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Photosynthesis provides oxygen in the atmosphere that support(s) much of the life on earth.

Photosynthesis is the process of producing one's own food. This process can be seen in plants, some bacteria and fungi. These organisms use the inorganic raw material like carbon dioxide, water and sunlight energy and produce food in the form of sugars, releasing oxygen as a by-product.

Oxygen is the most essential form of gas found in the earth. Majority of the organisms in the Earth are aerobic, that is they require oxygen for their survival. That is why oxygen supports much of the life on earth.

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suppose your group measures the following three numbers in some experiment: 12.4,7.8,10.2. if you use half the range as an estimate of the standard deviation, what is the standard error on the mean of these numbers? when you specialize in a task that you do best, you are applying the: a. law of demand. b. law of supply. c. law of absolute advantage. d. law of comparative advantage. Which of these best demonstrates mutualism between certain types of bacteria and humans Which element of the business model addresses why the customer should buy from you? Two trains are 150 km apart. train a moves at 50.0 km/hr towards train b, which moves at 30.0 km/hr toward train a on the same track. how much time do they have before the trains collide? The concentration of a was 0.65 m at 33 s. the initial concentration of a was ________ m. A and \angle BB are vertical angles. If m\angle A=(7x+22)^{\circ}A=(7x+22) and m\angle B=(8x+20)^{\circ}B=(8x+20) , then find the measure of \angle AA. According to the small business administration, over 50 percent of all small businesses are home based. true false Ratings and diagnoses from ____ are generally reliable across raters, and have high content validity because they are based on specific criteria. In a class of 30 students, 15 students have taken English, 10 students have taken English but not French. Find the number of students have taken: (i) French, and (ii) French but not English. Why do people say that ferdinand magellan circumnavigated the globe even though he died on the way?. Short-term fluctuations experienced in the economy due to changes in levels of economic activity describe the? Mandy has $40 in a savings account. The interest rate is 5%, compounded annually. To the nearest cent, how much will she have in 2 years Which inference can be made about the author's experience at the Lincoln School in Barrio Boy? part b Sodum has a work function of 2. 1eV and is illuminated by radiation whose wavelength the is 150mm, Calculate the maximumum energy. question 6. a nurse may not be reported to the bon, may not have his or her license sanctioned by the bon, and may not be suspended or terminated from his or her employment for either appropriately invoking safe harbor or for advising another nurse of their right to invoke safe harbor. these are a. criteria for determining a minor incident. b. rules that apply to rns and not lvns. c. safeguards that protect the nurse from all methods of retaliation. d. protections for a nurse who requests a peer review determination. What is the likelihood of a person developing schizophrenia if the disorder affects his or her fraternal twin? How would the likelihood change if DNA sequencing revealed that the twins shared the genetic variants that contribute to the disorder? 4. In what region of the periodic table are you likely to find elements that form more than one stableion? in the northern colonies, employers often saw free labor as more desirable than slave labor because of the generally accepted belief in northern economies that slavery was immoral. angle q and angle r are complementary. the measure of angle q is 26 degrees less than the measure of r. find the measure of each ang;e