The activity of the pyruvate dehydrogenase complex is also controlled by phosphorylation. Pyruvate dehydrogenase kinase (PDH kinase) catalyzes the phosphorylation of a specific Ser residue on the E1 subunit of the enzyme, rendering it inactive. Pyruvate dehydrogenase phosphatase (PDH phosphatase) reverses the inhibition by catalyzing the removal of this phosphate group. The PDH kinase is highly regulated and its activity is influenced by various cellular metabolites. Indicate whether the following would activate or inhibit PDH kinase:
Inhibit or activate PDK?
NAD+ activate
NADH inhibit
coenzyme A activate
acetyl-CoA inhibit
ADP inhibit
Did I answer these correctly?

Answers

Answer 1

Answer:

Increase in [NAD+] inhibits Pyruvate dehydrogenase kinase (PDH kinase)

Increase in [NADH] activates Pyruvate dehydrogenase kinase (PDH kinase)

Coenzyme A inhibits Pyruvate dehydrogenase kinase (PDH kinase)

Acetyl-co A activates Pyruvate dehydrogenase kinase (PDH kinase)

ADP inhibits Pyruvate dehydrogenase kinase (PDH kinase)

Explanation:

Pyruvate dehydrogenase kinase, PDK is an enzyme which acts to inhibit the activity of the enzyme pyruvate dehydrogenase by phosphorylating it using ATP. It mechanism of action is by catalyzing the phosphorylation of a specific Ser residue on the E1 subunit of the pyruvate dehydrogenase complex, rendering it inactive. By inhibiting the activity of the pyruvate dehydrogenase complex, PDK will decrease the oxidation of pyruvate to acpcetyl-coA and CO₂ in the mitochondria and increase the conversion of pyruvate to lactate in the cytosol.

Since pyruvate dehydrogenase complex is activated by either an increase in the concentration of one or more of ADP, NAD+ or CoA-SH, its inhibitor pyruvate dehydrogenase kinase is inhibited by ADP, NAD+, CoA-SH and pyruvate. However, PDK is activated by increase in the concentration of ATP, NADH and acetyl-CoA.

Therefore, the correct answers are:

Increase in [NAD+] inhibits Pyruvate dehydrogenase kinase (PDH kinase)

Increase in [NADH] activates Pyruvate dehydrogenase kinase (PDH kinase)

Coenzyme A inhibits Pyruvate dehydrogenase kinase (PDH kinase)

Acetyl-co A activates Pyruvate dehydrogenase kinase (PDH kinase)

ADP inhibits Pyruvate dehydrogenase kinase (PDH kinase)


Related Questions

A solid is that form of matter that possesses the following
characteristics __.
a
Particles vibrate around fixed axes
b Definite shape
C
Definite volume
d All of the above

Answers

Definite volume is doesn’t possess a definite volume so therefore the answer is c

What is a frog's habitat?
R. the flies that it eats
S. the green skin coloration
T. a forest pond
V. the total number of frogs in the area​

Answers

The answer is T
Expiation

In the ELISA procedure, first a protein sample is immobilized to a plastic well. Then, the antibody to the protein of interest is added, incubated, and the excess is washed out. Next, the detection antibody (which binds to the primary antibody) is added, incubated, and the excess is washed out. The last step is to add the detection dye (which binds to the detection antibody) to the wells and allow it to incubate. What do you predict the result would look like if you added the detection antibody first, then the antibody to the protein of interest

Answers

Answer:

In this ELISA procedure, a sample of protein is immobilized in the plastic well and then antibody for this protein added and incubated, and cleared out. In the given setting detection, the antibody is conjugated with the protein of interest and if the substrate molecule added to the reaction it will produce a colored product by reacting with the enzyme.

No reaction will take place in the well in case of not adding secondary antibody or detection antibody to the reaction and no colored product will be received.

is the long-term average weather over a large area

Answers

Climate is the long-term average weather conditions that occur in a particular region. Climate depends on how average weather conditions change throughout the year.

When parents reproduce, they pass different versions of genes, or _____, for different traits to their ____.

Answers

Answer:

characters

offsprings.

Explanation:

During meiosis, all various genes are separated. The inherited alleles constitute the genotype of the individual.

The transfer of parental to offspring characteristics is called heredity and the heritable features can be predicted.

Which of the following metabolic pathways does NOT directly produce lots of ATP (also called anaerobic cycle)?

A. Glycolysis
B. Krebs cycle
C. Citric acid cycle
D. Electron transport chain

Answers

Answer:

A. Glycolysis

Explanation:

Glycolysis is the first stage of cellular respiration, which occurs in the cytoplasm of the cell. Glycolysis does not require oxygen to occur, hence, it is carried out by both prokaryotic and eukaryotic organism.

Glycolysis, among the other stages of cellular respiration, produces the least ATP (2). Hence, Glycolysis is the metabolic pathway that does NOT directly produce lots of ATP.

How many objects must be present in a system to demonstrate gravity as a force of attraction?

Answers

Answer:

Explanation:

Knowing the value of G allows us to calculate the force of gravitational attraction between any two objects of known mass and known separation distance. As a first example, consider the following problem.

Which of the following is not considered to be a surface water?
A) aquifer
B)ponds
C)wetlands
D)river

Answers

Answer:

A) aquifer

Explanation:

surface waters are bodies of water that consist of water from rainfall etc, and aquifer does not consist of rainfall etc.

A pyramid of biomass shows the mass of all of the organisms in each trophic level of an ecosystem. Look at the biomass pyramid to the right. Based on the data shown, how many kilograms of plant matter would be needed to support the other trophic levels in this ecosystem?

Answers

Answer:

90,000

Explanation:

A pyramid of biomass shows the mass of all of the organisms in each trophic level of an ecosystem. From the biomass pyramid to the upright ladder, the kilograms of plant matter needed to support the other tropic levels in this ecosystem is 9000 kg.

In ecology, the biomass pyramid is a graphical representation designed to show the quantity of biological or organic matter observed in an organism.

The ecological biomass pyramid starts with the primary producer which is usually a green plant.

Followed by the herbivores(animals that feed) on the green plants. They are the primary consumers. The carnivores are secondary consumers that feed on herbivores. Then the peak of the pyramid is the tertiary consumers which are called omnivores. (i.e animals that feed on plants & animals).

The amount of mass consumed by the primary consumer is equivalent to the total amount of mass in the primary consumer. However, as we go up the pyramid, the mass depreciates.

Therefore, we can conclude that the amount of kilograms of plant matter needed to support the other tropic levels in this ecosystem is 9000 kg.

Learn more about Biomass here:

https://brainly.com/question/20572728?referrer=searchResults

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Look at the Density of Substances table. Which two substances from the table are buoyant in pure water?

A. silver and lead
B. lead and diamond
C. gasoline and ethyl alcohol
D. silver and diamond

Answers

{answer}
Silver and lead

{ I hope this helps :) }

Answer:

Silver and lead

Explanation: hope that helps

In this food web what is represented by the chains of arrows from the grass to the fox?

Answers

Answer:

Does anyone watch shaurya aur anokhi ki kahani on star plus an Indian serial you'll love it

Is a forest area that has been washed away by a flood a primary or secondary area of succession?

Answers

Answer:

I'm pretty sure it's secondary

Explanation:

Secondary succession is a major disturbance such as a fire or a flood

List 3 inputs (things entering) for the leaf in Model 1.

Answers

Answer:

light energy,carbon dioxide, and water

Explanation:

Answer:

light energy,carbon dioxide , water

common leaves dichotomous key lab report

Answers

Answer:

.

Explanation:

PLZZZZZ HELP WILL GIVE BRAINLIEST
NO LINKS!!
OR ELSE

A person is taken to the emergency room at Baptist Hospital vomiting, bleeding and with severe diarrhea. He complained of a headache, shortness of breath and body aches. The doctor quickly checked the composition of the patient’s blood plasma, the light-yellow liquid that carries salts and enzymes, and determined he was severely dehydrated. Thus, causing a severe loss of fluid in the blood and an increase of blood cell concentration. The doctor prescribed intravenous liquids (IV) and rest.

Based on the patient’s symptoms and doctor’s initial prognosis, how does dehydration affect a person’s blood flow and blood pressure? SC.912. L.14.36

The patient’s blood viscosity would increase, causing blood flow to increase and blood pressure to decrease

The patient’s blood viscosity would decrease, causing the blood flow and blood pressure to remain at a stable rhythm

The patient’s blood viscosity would decrease, causing the blood flow to decrease and the blood pressure to also decrease

The patient’s blood viscosity would increase, causing the blood flow to decrease and the blood pressure to increase

Answers

Answer:

The answer is "The patients blood viscosity would decrease, causing the blood flow to decrease in the blood pressure to also decrease".

The correct answer is: The patient’s blood viscosity would increase, causing the blood flow to decrease and the blood pressure to increase.

What is Dehydration?

When the body loses more fluid than it takes in, dehydration develops. It occurs when the quantity of water and electrolytes (such as sodium, potassium, and chloride) that the body need to operate correctly are out of balance.

Numerous internal processes, such as controlling body temperature, lubricating joints, transferring nutrients, and getting rid of waste, depend on water.

Dehydration causes the amount of fluid in the blood to decrease, which causes the concentration of blood cells and other components to rise.

Blood gets thicker and flows more slowly as a result of this rise in blood viscosity, which is caused by an increase in blood cell concentration.

As a result, the blood flow decreases, and the resistance to blood flow increases, leading to an increase in blood pressure.

Therefore, in the given scenario, the patient's severe dehydration would cause an increase in blood viscosity, leading to a decrease in blood flow and an increase in blood pressure.

Learn more about dehydration at:

https://brainly.com/question/12261974

#SPJ2

pls help me with answers due today

Answers

it's hard to read, can you crop out the rest so it's just the worksheet

There it is what is the answer

Answers

Answer:

I'm confused what's the question???

Where is the question at?

Search in the internet a picture that demonstrates a skill in harvesting/capturing animal/fish?. Paste the picture below.​

Answers

https://images.app.goo.gl/vCAczhDoFTzKwUit9 This picture demonstrates skill because the person is using multiple tools at once to capture fish.

Siphos brother is an actor.​

Answers

Answer:

good for siphos lol

Explanation:

1.
Which has the greatest impact on the temperature of the Earth's atmosphere?
chemical runoff
sulfur dioxide
carbon dioxide
Ozone

Answers

The answer is carbon dioxide.

what is noun ?what is verb?what is full from of cpu?​

Answers

Answer:

Noun:a word (other than a pronoun) used to identify any of a class of people, places, or things ( common noun ), or to name a particular one of these ( proper noun ).

Verb: a word used to describe an action, state, or occurrence, and forming the main part of the predicate of a sentence, such as hear, become, happen.

Central processing unit (CPU), principal part of any digital computer system, generally composed of the main memory, control unit, and arithmetic-logic unit. ...

Answer:

Noun

Noun is a naming word .

Verb

verb is an action word .

The full form of CPU is central processing unit .

hope it is helpful to you


Which of the following are true of scientific hypotheses?
(Check all that apply.)
They can represent someone's opinion about why change occurs.
O They can be tested through observations of natural events.
O They must be rejected if no evidence is found to support them.
They must be agreed upon by all scientists before they are tested.
15 of 19
NEXT >
PREVIOUS

Answers

Answer:

I think it's these two

O They can be tested through observations of natural events.

O They must be rejected if no evidence is found to support them

please help

There are many different chordates. Choose fifteen chordates to explore. As you explore fill in the chordate chart that can be downloaded below. For each chordate you will need to check if it is a vertebrate or invertebrate, when in its life cycle did it have a notochord, when in its life cycle did it have gill slits and note any other interesting fact about your animal.

Answers

Answer:

Giraffe - vertebrate

white tiger - vertebrate

In humans, nearly 80% of proteins are acetylated on their N-terminal residue, a modification known to be recognized by a specific E3 enzyme, which directs the ubiquitylation of the protein for rapid degradation. Does this mean that all of these proteins would be actively degraded at the same time

Answers

Answer:

Yes

Explanation:

Yes this means that all of these proteins will be actively degraded and this is due to the high turnover rate which will ensure that their activity will be under tight control.

The acetylation of the N-terminal of the protein, with the Ubiquitylation of the protein by an E3 enzyme, helps in the maintenance of the homeostasis of protein activity.

Group the following into the appropriate range of measurement.
a. atomic
b. ultramicroscopic
c. microscopic
d. macroscopic
Match each of the options above to the items below.
1. roundworm, algae
2. protozoan, rickettsia
3. herpesvirus, DNA
4. hydrogen atom, glucose molecule

Answers

Answer:

Hydrogen atom & glucose molecule --- atomic.

Herpesvirus, DNA --- ultramicroscopic.

Protozoan, Rickettsia - microscopic.

Roundworm and algae --- macroscopic

Explanation:

1) Hydrogen atom & glucose molecule --- atomic.

The atomic size level, which interacts with atoms as well as small molecules, is much lower than the ultramicroscopic range.

2) Herpesvirus, DNA --- ultramicroscopic.

Ultramicroscopic particles are very tiny structures that cannot be seen using a conventional optical microscope, necessitating the use of an electron microscope. Viruses and DNA falls into this group since they are much smaller than tiny species like bacteria.

3) Protozoan, Rickettsia - microscopic.

Microscopic species are much smaller than macroscopic organisms because they cannot be observed by the naked human eye and must be viewed through a microscope. The size range for microscopic particles is [tex]( 10^3 \ \ to \ \ 10^{10})[/tex], which contains protozoans and Rickettsia (a gram-negative, non-motile bacteria genus).

4) Roundworm and algae --- macroscopic

Naked eyes can see macroscopic organisms; for example, several types of circular worms and algae can be seen by them.

Which of the following best describes an environmental advantage of urbanization?
А
Individuals living in cities have more varied employment opportunities than individuals living in rural areas.
B
Individuals living in cities have greater access to health care than individuals living in rural areas.
с
Individuals living in cities usually have greater access to fresh, local agricultural products than individuals living in rural areas.
D
Individuals living in cities usually have a lower transportation carbon footprint than individuals living in rural areas.

Answers

D
Answer: A I am sure of Ik
Wallahi it will be so cool

Individuals living in cities have more varied employment opportunities than

individuals living in rural areas is an environmental advantage of

urbanization.

Urbanization involves the increase in the industrialization thereby leading

to the increase in population to the area. Cities usually have a higher

degree of urbanization due to presence of various industries and access to

the best facilities.

The increase in industries during urbanization makes varied employment

opportunities present and an advantage over the rural areas.

Read more on https://brainly.com/question/2277541

help pls for brainliest

Answers

Answer:

There are two people affected

Explanation:

The black shapes are affected people, the white ones are unaffected

6. A bus travels down a straight highway and goes from 0 to 10m/s in 5 seconds.

What is its acceleration?

a. 2m/s2

b. 3m/s2

c. 4m/s2

d. 5m/s2 7. A car can travel 50 meters in 10 seconds. A fast motor bike can travel 5 meters

in a second. A bus can cover 500 meters in 100 seconds. Which vehicle has the

highest speed?

a. The car has the highest speed because it travels a great distance in a

short time.

b. The bus has the highest speed because it can travel the greatest distance.

c. The bike has the highest speed because it has the shortest travel time.

d. All their speeds are equal.

8. Which of the following is TRUE about speed and velocity?

a. Speed is a vector and velocity is scalar.

b. Velocity is the speed in a particular direction.

c. An object can accelerate even if the velocity is constant.

d. A change in speed causes an acceleration. A change in velocity causes

deceleration.

9. A bicycle has an average speed of 2m/s. This means that _________.

a. in 1 second, it travels 1 meter

b. it can travel 4 meters in 2 seconds

c. it takes 2 seconds to travel 1 meter

d. it can travel 2 kilometers in one hour

10.An object can accelerate while moving at constant speed. Which situation

illustrates this?

a. A roller coaster making a fast dive.

b. A bus going uphill at constant speed.

c. A bump car going in circles at constant speed.

d. A car moving down a straight highway at constant speed.​

Answers

Answer:

6) 2m/s²

7)All the speeds are equal

8) Velocity is speed in a particular direction

9) it can travel 4 m in 2 sec

10)a bus going uphill at constant speed (not sure abt this)

Why does the mass of a substance remain the same after a chemical reaction

Answers

Answer:

Even in a chemical reaction when atoms interact and create new products, mass is conserved. This is because the new substances created are composed of atoms that were present in the reactants. The atoms from the reactants come apart, rearrange, and re-bond in a different arrangement to form the products.

1. Elmo has big nose, and his wife Zoe has a little nose. All of their babies have medium size noses. Is nose size determined by alleles that show regular dominance, incomplete dominance, or codominance? Pick a symbol for the big nose allele ______ Pick a symbol for the little nose allele______

Answers

Answer:

codominance

Explanation:

Big nose could be N and little nose could be n.

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Milford Company sells a motor that carries a three-month unconditional warranty against product failure. Based on a reliable statistical analysis, Milford knows that between the sale and the end of the product warranty period, two percent of the units sold will require repair at an average cost of $50 per unit. The following data reflect Milford's recent experience: Oct Nov Dec Dec 31 TotalUnits unsold 24000 26000 26000 76000Known products failure from sales in:October 130 190 170 490November 130 220 350December 210 210 Calculate, and prepare a journal entry to record, the estimated liability for product warranties at December 31. Assume that warranty costs of known failures have already been reflected in the records. Two sides of a triangle measure 8 cm and 15 cm. Whi[:h could be the length of the third side?O 6 cmO 18 cmO 24 cmO 28 cm One side of a rectangle is parallel to the x-axis. One vertex of the rectangle is located at (5,2) and another vertex at (1,4). What are the coordinates of the other two vertices? !!!!NEED HELP ASAP DUE SOON!!!!!This table of values represents a linear function. Enter an equation that represents the function defined by this table of values. PLEASE HELP!!!!! (screenshot) Which of the following is/are true about kanban? A. The purpose of the kanban system is to ensure that parts are produced JIT to support subsequent processes. B. Some companies control the movement of the containers by using two types of kanban cards, production cards and withdrawal cards. C. Kanban cards take the place of shop paperwork used in traditional repetitive mass production. D. a and b are true goodmorning wonderful peoplee Which of the following is the reason in how the anterior pituitary differs from theposterior pituitary?O A) the hypothalamus controls the release of posterior pituitary hormones but not the anteriorpituitaryB) the anterior pituitary makes its own hormones; the posterior pituitary releases hypothalamichormonesC) the posterior pituitary works independently of the hypothalamusD) the anterior stores hormones produced by the posterior pituitary Please help.Is algebra. Should students be able to substitute an art or music class for a PE class in school? GIVING BRAINLIESTLook at the stem-and-leaf plot. What is the mode?A) 0B) 1C) 20D) 31 no link need right answer for usatestprep what do i do if my mother treats my older and younger (im the middle child) siblings wayyyyy better than me? my mom lets my older and younger siblings get whatever they want and she doesn't hit them/pokes them like she does me. She got my sister $300 worth of stuff when she got me nothing and she got my older brother a monitor and a big desk. she aslo got my younger siblings devices when i dont even have one. i cant live like this anymore she says she wants me to feel loved but all she does is calls me a b**** and rude names how am i supposed to feel loved Bart owns a neighborhood Kwik-E-Mart. At the end of the day on Wednesday, he counted total receipts in his store of $8,399.70. If the sales tax on food items is 2%, how much merchandise did Bart sell on Wednesday? How much sales tax did he collect? An Inconvenient Truth: A Global Warming-What type of radiation is given off by the Earth? Why is it important that Earth trap some of this radiation? 6What do greenhouse gases (CO2) do to the atmosphere? Who was one of the first scientists to realize the effects of CO2 in the atmosphere? When did he do this? How was it measured? Where? Why does a graph of CO2 emissions through time have annual fluctuations that correspond with the seasons? Why are glaciers in the Himalayas so important? How can scientists tell what CO2 levels were like in the past? I give Brainliest! Please No Links! What are Good Dance Songs? A 150 g pinball rolls towards a springloaded launching rod with a velocity of 2.0 m/s to the west. The launching rod strikes the pinball and causes it to move in the opposite direction with a velocity of 10.0 m/s. What impulse was delivered to the pinball by the launcher? Im giving brainliest GIVING BRAINLIEST! WHAT IS ATMOSPHERE? Each glass vase at a Mothers Day brunch has 8 stems, of which 37.5% are stems of greenery. How many stems of greenery are in each vase?