PLEASE HELP!!! WILL MARK AS BRAINLIEST!!! D:
A. SICKLE CELL ANEMIA: GENETICS AND EVOLUTION

Circle the mutation in DNA of the sickle-cell beta-globin gene fragment in the table below:
Wild-type beta-globin gene fragment
C A C G T A G A C T G A G G A C T C

Sickle-cell beta-globin gene fragment
C A C G T A G A C T G A G G A C A C


Transcribe beta-globin DNA into mRNA. Note: DNA is already arranged in triplet sets (below).

Translate mRNA codons into amino acids of hemoglobin protein sequence using the chart on page 3.



Wild-type beta-globin gene fragment
C A C G T A G A C T G A G G A C T C

Transcription produces mRNA fragment:
Translation produces wild-type beta-globin polypeptide fragment:

Sickle-cell beta-globin gene fragment
C A C G T A G A C T G A G G A C A C

Transcription produces mRNA fragment:
Translation produces mutant beta-globin polypeptide fragment:

Answers

Answer 1

In this example an adenine replaces a thymine. Wild-type mRNA  GUGCAUCUGACUCCUGAG/ Protein Val-His-Leu-Thr-Pro-Glu. Mutated mRNA GUGCAUCUGACUCCUGUG/ Protein Val-His-Leu-Thr-Pro-Val.  

--------------------------

Mutations are changes that occur in DNI nucleotide sequences that introduce new variants.

There are different types of mutations. In the exposed example, the last thymine from the Wild-type beta-globin gene fragment is replaced by an adenine in the Sickle-cell beta-globin gene fragment. The other bases remain equal.

Wild-type gene fragment    ⇒     C A C G T A G A C T G A G G A C T C

Sickle-cell gene fragment   ⇒     C A C G T A G A C T G A G G A C A C

Wild-type beta-globin gene fragment

Transcription

Transcription occurs in the nucleus. In RNA uracil replaces thymine.

While growing mRNA molecule,

adenine pairs uracil, thymine pairs adenine, and guanine pairs cytosine.

DNA    ⇒    C A C G T A G A C T G A G G A C T C

mRNA  ⇒   G U G C A U C U G A C U C C U G A G

Translation

Translation occurs in the cytosol. mRNA codons codify for amino acids.

Codons have been separated by a space.

mRNA  ⇒   G U G      C A U          C U G           A C U       C C U      G A G

Protein ⇒  Valine  -  Histidine  -  Leucine  -  Threonine - Proline - Glutamine

Sickle-cell beta-globin gene fragment

Transcription

DNA    ⇒   C A C G T A G A C T G A G G A C A C

mRNA ⇒   G U G C A U C U G A C U C C U G U G

Translation

mRNA  ⇒   G U G      C A U         C U G           A C U         C C U     G U G

Protein ⇒  Valine  -  Histidine  -  Leucine  -  Threonine - Proline -  Valine

---------------------------------------

Related link: https://brainly.com/question/9598940?referrer=searchResults

                     https://brainly.com/question/13923224?referrer=searchResults

                     


Related Questions

Several color variants of a wild berry are shown below in which black is the wild-type phenotype. All of the color variants are due to differing alleles for the same gene. Crosses produce the following results:

Based on the results above, which FOUR of the following statements are true?
• The green color is recessive.
• The green color is dominant to the wild-type black color.
• The blue color is recessive to the wild-type black color.
• The blue color is dominant.
• The blue color is recessive to the green color.
• The green color is recessive to the blue color.
• The blue color is recessive.
• The blue color is dominant to the green color.
• The green color is recessive to the wild-type black color.
• The blue color is dominant to the wild-type black color.
• The green color is dominant to the blue color.
• The green color is dominant

Answers

Answer:

the green colour is recessive

ens
Question 4
ents
allery
Which of the following is not a Learning Style:
O Auditory
O Visual
Kinesthetic
O Sculpting
1 nto
WIN
Ollection 5
na ml_ex3_5.pdf
por ml_ex4_1.pdf
DOF ml ex4_2.pdf
N
POF ml_ex4_3.pdf
57°F Cle
Si
to search

Answers

Answer:

HUH? I THINK THIS IS HAVE NO IDEA IN ANSWER CAUSE THE QUESTION IS NOT INCLUDED

2. According to the graph below, what temperature will result in the highest rate of photosynthesis?
1004 Oxygen flow (ml)
80
50
40
20
0
0
Temperature (1)
50
10
20
30
40
O A 5°C
OB. 40°C
O C.30°C
O D. 25°C

Answers

Answer:

At medium temperatures, between 50 and 68 degrees Fahrenheit, or 10 and 20 degrees Celsius, the photosynthetic enzymes work at their optimum levels, so photosynthesis rates gauge high. Depending on the particular plant in question, set the greenhouse thermostat to a temperature within this range for best

In gymnastics, a gymnast must be able to balance on a balance beam. What is the best explanation for what forces are acting on the gymnast on a balance beam? (2 points)



The forces are balanced when the force of gravity pulling you down is the same as the force of the balance beam pushing you up.

The forces are unbalanced when the force of gravity pulling you down is the same as the force of your legs pushing you up.

The forces are balanced when the force of gravity pulling you down is stronger than the force of the balance beam pushing you up.

The forces are unbalanced when the force of gravity is reduced to the same force as the balance beam pushing you up.

Answers

Answer:1

Explanation:Because gravity always pulls you down even when your standing on an object.

Which of the following is true about the sugar molecules in plants

1. The sugar molecules are made by plants and animals for energy

2. The sugar molecules are the result of a chemical reaction called photosynthesis

3. The sugar molecules are used by the cells as energy

4. The sugar molecules are made from molecules of water and carbon dioxide during cellular respiration

Answers

Answer:

2

Explanation:

Plants make sugar from the sun, water, and carbon dioxide in the air. a chemicls reaction happens causing photosynthesis

Most species of animals do not
drink milk once they have
reached adulthood. Which of
these is an animal that DOES
continue to drink milk into
adulthood?
A. humans
B. snakes
C. spiders

Answers

your answer will be C. spiders

Answer:

if we don't know anything about animals we can say that snakes and spiders complete itself development in an egg.the possible answer is A

can someone answer it! ​

Answers

The answer is because: What is meant by Na+ channel inactivation? The Na+ channel no longer allows Na+ ions to pass through it. What happens when voltage-gated K+ channels open? ... minimum voltage needed to generate an action potential.

why could the formation of a hole in the ozone layer cause concern?​

Answers

Answer:

Because it can damage the protective layer in the earth's atmosphere, therefor causing a risk of high damage from meteorites and asteroids.

Explanation:

The formation of a hole in the ozone layer would cause concern because it increases the amount of ultraviolet rays that reach Earth and can harm it's inhabitants.

The magic word is:


A) Ostoma


B) cristae


C) chemiosmosis


D) chromosome


E) aneuploidy


F) gene


G) meristem


H) zygote

Answers

Please give more information, I can help if I know what it’s going for :)

Explanation:

Dear questioner;

Paddington's Answer is B)Cristae he see in his book

Hope it helps I'm a Paddington lover

When mRNAs are being translated simultaneously by multiple ribosomes, the structure is known as a(n) g

Answers

Answer:

The structure is known as polysome

What is the only thing recycled during the ATP-ADP cycle? *
О
ADP
ОАТР
O Glucose
Sugar Ring

Answers

Your answer would be Glusose

Name three reasons, as to why, bacteria is so widespread into different life/ecosystems​

Answers

Answer:

Bacteria are decomposers which break down dead material and recycle it. They also can be producers, making food from sunlight, such as photosynthetic bacteria, or chemicals, such as chemosynthetic bacteria.The most influential bacteria for life on Earth are found in the soil, sediments and seas. Well known functions of these are to provide nutrients like nitrogen and phosphorus to plants as well as producing growth hormones. By decomposing dead organic matter, they contribute to soil structure and the cycles of nature. Decomposers play a critical role in the flow of energy through an ecosystem. They break apart dead organisms into simpler inorganic materials, making nutrients available to primary producers.

Explanation:

using example, explain the concept of homeostasis

Answers

Answer:

Homeostatis: maintenance of constant internal environment (optimum temperature or optimum optimum osmotic concentration) that permits all the biochemical reactions and physiological functions to proceed with maximum efficiency.

▪For example, when we exercise, there is heat production in the body and the body temperature rises which gets detected by the nerve sensors present in the body and the temperature control system in the brain is activated. It then activates sweat glands that helps in bringing the body temperature back to normal.

What is special about each organism in the ecosystem

Answers

Here the answer ⬇️⬇️ thanks me later

What are the four things that plants need to live

Answers

Answer:

Sunlight, water, carbon dioxide, dirt/soil

Explanation:

SunlightAirWaterSouce of nutritionOptimal Temperature

Crossing-over occurs in prophase of mitosis and meiosis.
True
False

Answers

It is True crossing over occurs in prophase of mitosis and meiosis

Hey, I need help with these questions please:

Answers

Answer:

D

Explanation:

can you please help?​

Answers

Answer:

it's b

hope it will help you

What other food do plantains resemble?

A.
sweet potatoes

B.
bananas

C.
white potatoes

D.
beets

Answers

Answer:

B.  bananas

Explanation:

f the daughter cell contains 24 chromosomes, how many were contained in the parent cell, for Mitosis and Meiosis?

Answers

Answer:

The answer to your question depends on whether cells are dividing after mitosis or meiosis. I will give explanations for both.

During mitosis, the nuclear content of the cells divides just prior to cytokinesis when the cell itself divides. Prior to mitosis, the DNA contained in the parent cell is...

Explanation:

KERE ON LEARNING?

Which structure is most directly responsible for maintain homeostasis in all the cells?

Answers

Answer:

Cell membrane or plasma membrane is most directly responsible for maintain homeostatis in all cells.

Suggest an explanation for the evolution of the pigeon-like ancestor into the flightless dodo.

Answers

Answer:

It's ancestors were pigeon-like birds which flew to the island millions of years ago. There were no predators on the island. Gradually, the birds became much heavier, lost their ability to fly and evolved into the dodo.

Explanation:

What is eutrophication ?​

Answers

Eutrophication is the process by which an entire body of water, or parts of it, becomes progressively enriched with minerals and nutrients. It has also been defined as "nutrient-induced increase in phytoplankton productivity".

Answer:

excessive richness of nutrients in a lake or other body of water, frequently due to runoff from the land, which causes a dense growth of plant life and death of animal life from lack of oxygen.

Explanation:

Hope it help

Why are braided streams common in sedimentary rocks before the arrival of plants on land ?

Answers

Answer:

Braided rivers have a multithreaded plan form comprising many confluences and diffluences (Miall, 1977). Braid bars and channels can be classified as a hierarchy depending upon their relative size, and three orders of braiding can be seen in proglacial rivers with constant discharge. First-order braid bars are those largest bars which are separated by major channels. First-order bars are made up of a series of smaller, second-order braid bars, which are separated by smaller channels. Third-order braid bars are contained within second-order bars. Complexity of braid pattern is, however, strongly stage dependent, with rivers losing their braided character during peak flood conditions. Braid bars, mid-channel bars, unit bars, and islands have been described in braided river systems on a range of scales ranging from meters to kilometers. All bars are subject to dissection , remobilization, and migration by the appropriate discharge magnitude and frequency (Miall, 1977, 1983).

Explanation:

Explain the use of oxytocin in labor inductoin in the case of obstructed labor

Answers

Oxytocin is commonly used in modern obstetric practice to increase uterine activity, in cases in which the labor process has failed, with the aim to enable it to progress to a vaginal delivery 3 .

Describe DNA replication. Include all relevant aspects. When does this process occur? and why

Answers

Replication is the process by which a double-stranded DNA molecule is copied to produce two identical DNA molecules. DNA replication is one of the most basic processes that occurs within a cell. ... To accomplish this, each strand of existing DNA acts as a template for replication.

A program designed to interfere with your computer, device or network's normal operation is called a Answer

Answers

Answer:

A virus

Explanation:

which describes the Grand canyon as it will be one million years from today?​

Answers

Answer:

I think it will become shallower and narrower.  

Explanation:

This is because today, the Grand Canyon is deep and wide, we are talking about how it was one million years ago, which would look noting like this today. Little piece of rock has started to fall off of the sides of the Grand Canyon so it looks how it looks today.  

hope it helps

aside from the hard-boiled egg, what other things can you compare to the earth's interior layer

Answers

Answer:

The Avocado because its seed represents its core and the avocado meat represents the mantle and the skin of the avocado represents the crust

Explanation:

Hope it Helps

Answer:

An Avocado can be another example

Explanation:

A window display attracts passersby
True
False

Answers

Answer:

it is dosnt attracts passerby False

Other Questions
Write the function of nucleus in the cells of organism If a jacket cost $74.95 and you had a coupon for 30% off, how much would the jacket cost you? (round to the nearest hundredth) Answer value 7/8 rounded to the nearest thousand where is the griswold house from christmas vacation Which pair of words correctly completes this conversation?Francisco: Mi auto es rpido.Emily: Mi auto es ______ rpido _____ el tuyo.A. mejor, msB. el, delC. menos, mayorD. ms, que Time went scuba diving and descended at a rate of 35 feet every 20 min. If Tim was diving from 11:00AM to 12:00PM. What was Tim's altitude at 11:40AM? write 28 + 24 as a product of two factors using the greatest common factor and the distributive property A stomp rocket takes 3.1 seconds to reach its maximum height. - What is its initial velocity? (Do not use units. If the answer is negative, please put a negative sign in front of the answer.)- What is its maximum height? (Do not use units. If the answer is negative, please put a negative sign in front of the answer.) The salt which in solution gives a pale green precipitate with sodium hydroxide solutionanda white precipitate with barium chloride solution is? The original quantity is 10 and the new quantityis 13. What is the percent change? Is it anincrease or decree? What might scientists learn about the evolution of human behavior from studying cognitive behavior in animals? Which best explains why major media formats, like television and film, are regulated by government agencies?A. Media can be quite influential, so it needs standards.B. Most people believe everything that the media reports.C. Without regulation, there would be no need for government.D. Advertisers do not want their products associated with certain stories. what is the most popular medication for high blood pressure? To prevent cross-contamination between solid dosage forms like tablets and capsules, a pharmacy technician should: What is the difference between slavery in Ancient Egypt and the Americas (Carribbean, South & North America) how to evaluate (-1/2)(-4) Find the vertices of the dilated figure whose original coordinates are A (0, 0), B (0, 9), C (8, 8) and D (10, 0) which is dilated by a scale factor of 6.A' (0, 0), B' (0, 54), C' (48, 48), and D' (60, 0)A' (0, 0), B' (0, -54), C' (-48, 48), and D' (60, 0)A' (0, 0), B' (0, 54), C' (48, -48), and D' (60, 0)A' (0, 0), B' (0, 54), C' (48, 48), and D' (-60, 0) Which is a program that requires providers to adhere to managed care provisions 4(2x - 1) + 3(2x + 5) 1) What is the author's purpose in writing this speech?A) describeB) entertainC) informD) persuade