I need help with this please.
Answer:
saya tidak tahu bahasa Inggris
What is the key activating signal in the TNF receptor signaling pathway that occurs downstream of TNF-alpha binding to the extracellular domain
Answer:
TNF-alpha is expressed as a homotrimer that exerts its activities through binding to two types of receptors: TNFR1 and TNFR2, which are transmembrane glycoproteins characterized by having an extracellular domain with 4 cysteine-rich domains (CRD 1-4) , each with 3 cysteinecysteine disulfide bonds.
Explanation:
TNF-alpha (Tumor Necrosis Factor), which has the characteristic of being a paracrine signaling ligand, is a pleiotropic cytokine that functions as a mediator of immune regulation, the inflammatory response and apoptosis in some cell types. Receptors in this family are involved, with some exceptions, in juxtacrine signaling; that is, both the ligand and the receptor are membrane proteins with extracellular domains through which signaling is established. The cellular responses promoted by TNF are initiated by its interaction with two different types of cell receptors, the type I receptor (55 kDa) and the type II receptor (75 kDa). Both types of receptors are part of the TNF receptor family, members of which include Fas antigen (apoptosis inducer, also called Apo-1 or CD95), CD27 (T-cell activation antigen), CD30 (lymphoma marker Hodgkin) and CD40 (B-cell antigen), which share the characteristic of cysteine-rich sequences in their extracellular domains. This family of cytokines generate cellular responses that include differentiation, proliferation, activation of NFκB and cell death, promoting the aggregation of receptor monomers, that is, they have a transmembrane domain that participates in the solubilization of the receptor and a domain of intracellular death that is involved in signal transduction. The binding of TNF to TNF-R1 induces a signaling cascade through its intracellular death domain, which subsequently leads to the activation of complex I (or inflammatory) of NFkB and proceeds to the transcription of anti-apoptotic genes, pro- inflammatory diseases and apoptosis complex II (caspases).
Select the correct answer.
The graph shows the percentage of dog breeds affected by elbow dysplasia, which causes dogs to limp. What’s the most likely explanation for the mixed breed’s disease incidence?
A. It has low diversity in its genes.
B. It has high diversity in its genes.
C. It’s good at saving human lives.
D. It doesn’t suffer attacks from wild predators.
E. It lives comfortably with people.
Answer:
B would be the answer
Explanation:
Fill in the blanks to complete these sentences about rock characterstics A rock is an of minerals of a rock is a result of its mineral composition Most rocks contain more than one type of The
Answer:
More than one t Type of mineral
Answer:
1)aggregate
2)color
3)mineral
Explanation:
Earth makes one full rotation on its axis approximately every 24 hours. If Earth's period of rotation decreased to 20 hours, which of the following changes would occur?
There would be fewer days in a week.
The length of nighttime would increase.
It would take Earth longer to revolve around the Sun.
The length of daylight and nighttime would decrease.
Answer:
The length of daylight and nighttime would decrease.
Explanation:
If 24 hours was decreased to 20, it would shorten night and day time.
Why is it important for nerve impulses to travel rapidly?
Answer:
The messages carried by neurons are called nerve impulses. Nerve impulses can travel very quickly because they are electrical impulses. ... The sheath covers the axon, like the plastic covering on an electrical wire, and allows nerve impulses to travel faster along the axon.
Answer:
The messages carried by neurons are called nerve impulses. Nerve impulses can travel very quickly because they are electrical impulses. ... The sheath covers the axon, like the plastic covering on an electrical wire, and allows nerve impulses to travel faster along the axon.
Cilia
Click through the images to
answer the questions.
4. Which type of microscope
produced the image of cilia?
5. What type of microscope
would be best for studying cilia
Answer:
Scanning electron microscope and electron microscope.
Explanation:
Scanning electron microscope is a type of microscope which can produced the image of cilia. Electron microscope is a type of microscope would be the best for studying cilia because it has higher magnification power i. e. 10,000,000x, which able us to study different parts of cilia so we can say that electron microscope is the right choice for studying cilia.
Classification of animals is done why
an atom that has gained or lost one or more electrons
This is called an ion. :)
Question 9 of 10
Which process is a form of mechanical weathering?
Explanation:
abrasion, pressure release, thermal expansion and contraction and crystal growth.
Help!
Good coping skills involve.
A. suppressing emotions.
B. managing emotions.
C. giving into emotions.
Answer:
B
Explanation:
Answer: B
Explanation: Managing emotions is actually healthy, being able to control how you feel about a certain topic will make life much easier. Practicing this will only help in the future. Suppressing emotions will only stress you out more. Giving into emotions is obviously going in the wrong direction, don't give up.
A common question you'll need to answer is "What is the relationship between the independent
variable) and (the dependent variable)?" In other words, as you change the variable that you're
testing, what is the outcome?
- So in this case, what is the relationship between time and the diameter of the trees?
HELP PLZZZZZ
Answer:
viton
Explanation:
viton
What is and example of an molecule
Muscle tissue
Protein
Stomach
Unicellular organism
where do the microtubules of the spindle originate during mitosis in both plant and animal cells ??
The rate at which a stars burns its fuel (gas) is based on the star's
Mass
Volume
Shape
Color
Answer:
based on the mass of the star
what does the phrase "science is not done" mean?
Answer:
yrfquwrfbliueiurviurnfr
Explanation:
that means i do not know what that means
how does a beneficial trait increases an organism's survival and potential reproductive success.
Answer:
This cumbersome trait significantly decreases the male's chances of survival. ... natural selection: that is, that organisms better adapted to their environment would benefit from ... the individual's reproductive success, even at the expense of their survival (Darwin 1871). ... A successful male can potentially sire many offspring.
Explanation:
The beneficial trait increase the survival and potential reproductive success of the organism as they help organism to thrive in their unfavorable changing environment.
Natural selectionThe natural selection can be defined as the differential survival and reproduction of those organisms which have beneficial traits over others.For example, the color change in chameleon helps them to remain undetected from predator population as well as from prey so it helps in increase in rate of survival of chameleon also helps them to reproduce and increase in number.Hence, beneficial traits increase the rate of survival and reproduction of organisms.
Learn more about natural selection:
https://brainly.com/question/9830102
look at the picture
why would an athlete need to be concerned about a twitch or sustained contraction
Answer:
why an athlete would need to be concerned about twitches or contractions is because, whenever they perform, and such thing happens, it will most likely distract the athlete, and cause the athlete doing his/her performance to not be as good, and may lead to failure, for example, when someone is running very fast for a sprinting race, and he has a contraction in his leg it will cause him to react by showing signs of pain by slowing down or even tripping and falling, causing him to lose the race.
Hope this Helped!
Plants, algae in some bacteria use the energy of sunlight in the process of what
Answer: Photosynthesis
Explanation: takes in the carbon dioxide produced by all breathing organisms and reintroduces oxygen into the atmosphere. Photosynthesis is the process used by plants, algae and certain bacteria to harness energy from sunlight and turn it into chemical energy.
Answer:
photosynthesis
Explanation:
hope it helps. if you need an explanation on what that is let me know!
PLEASE HELP ASAP (; question in photo
Answer:
im like 99% sure its D
Explanation:
im sorry if its wrong :(
STOP RIGHT NOW. Hello.. Help me with this question.. Please?
Answer:
its A, B and D
Explanation:
Precipitation falls to the ground and eventually ends up in the ocean. Which of the following is the most direct way for the water to get from the soil to the ocean? A. By way of a recharge zone with a low percolation rate B. By way of a closed watershed C. By way of an open watershed D. By way of thermohaline circulation within an aquifer
Answer: D. By way of thermohaline circulation within an aquifer
Explanation: The most direct way for the water to get from the soil to the ocean is by way of a recharge zone with a low percolation rate. Human activity in the recharge zone can limit the amount water that reaches the aquifer.
All of the following are true of spermatogenesis EXCEPT: Question 4 options: One spermatogonium produces 4 spermatids Genetically diverse spermatids are created. The products are spermatozoa that each have a head, midpiece and tail. DNA replicates once, but cells divide twice. Spermatids containing 23 chromosomes (1n) are produced.
Answer: The products are spermatozoa that each have a head, midpiece and tail.
Explanation:
The spermatogenesis can be defined as the process of gamete production in human males. It takes place in the testes in males. In this process the spermatids are produced which are four in number through reductional cell division called as meiosis. Each spermatid is haploid in number and the genetic material present in each is diverse as a result siblings are not identical to each other. The spermatozoa is an immature sperm cell which develops head, middle piece and tail. But it is not a precursor of production of sperm cells via cell division.
What are the reactants for photosynthesis?
Answer:
well the chloroplasts are the part of the cell that make photosynthesis happen
Answer:
light energy, water, carbon dioxide, and chlorophyll.
Explanation:
Which populations are least affected by density-dependent factors?
What's the definition of absoulute dating
Absolute dating is the process of determining an age on a specified time scale in archaeology and geology. Some scientists prefer the terms chronometric or calendar dating, as use of the word "absolute" implies an unwarranted certainty and precision. Absolute dating provides a numerical age or range in contrast with relative dating which places events in order without any measure of the age between events. In archeology, absolute dating is usually based on the physical, chemical, and life properties of the materials of artifacts, buildings, or other items that have been modified by humans and by historical associations with materials with known dates. Techniques include tree rings in timbers, radiocarbon dating of wood or bones, and trapped charge dating methods such as thermoluminescence dating of glazed ceramics. Coins found in excavations may have their production date written on them, or their may be written records describing the coin and when it was used, allowing the site to be associated with a particular calendar year.
5. What would be the effect if a gene has a mutation in the location of the stop codon? (4 points)
During translation protein synthesis won't stop when it should so amino acids will continue to be placed and the peptide will be bigger.
Answer:
In genetics, a point-nonsense mutation is a point mutation in a sequence of DNA that results in a premature stop codon, or a point-nonsense codon in the transcribed mRNA, and in a truncated, incomplete, and usually nonfunctional protein product.
What is the major difference during cytokinesis in eukaryotes with or without a cell wall?
Answer:
Cytokinesis in eukaryotic animal cells do not have a cell wall, it occurs through a strangulation process carried out from the plasma membrane, this process is called segmentation. Plant cells are characterized by cytokinesis based on septate, since the cell wall does not allow strangulation.
Explanation:
Cytokinesis means: cell division, it is a cellular process parallel to mitosis whose purpose is the division of the stem cell's cytoplasm between daughter cells. In animal cells, cytokinesis occurs by cleavage. At the end of anaphase and during telophase, the central part of the cell narrows, forming the segmentation groove, which deepens (strangulation). Plant cells, as they lack centrosomes, will form the achromatic spindle from two polar caps. In this case, cytokinesis does not occur by strangulation, but a cell wall is formed between the two daughter cells. This septum, called a fragmoplast, is formed from vesicles from the Golgi apparatus.
The major difference during cytokinesis in eukaryotes with or without a cell
wall is in the formation of cell plate in cells with cell wall while in animal
cells cytokinesis occurs through the formation of a cleavage furrow.
Cytokinesis is the process of cell division in which the cytoplasm divides
into two. Plants have cell walls while animals lack cell walls.
Animal and plant cells form cleavage furrow and cell plate respectively
which aids division into two equal parts.
Read more about Cytokinesis here https://brainly.com/question/5615155
does anyone know this pls help
Answer:
A person standing on the ground is barely affected by surface gravity